Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity linked to bortezomib, a proteasome inhibitor Utilized in the procedure of numerous myeloma. Its synthesis or research is crucial for making sure the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor in the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-ten-one): A crucial compound during the synthesis of imatinib, a drug that targets unique types of cancer, which includes Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are definitely intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their research is essential for optimizing the manufacturing system and making sure superior purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is used to take care of breast cancer, and these intermediates are linked to its generation.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist used in the procedure of breast cancer. Several intermediates help in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers including ovarian, breast, and lung most cancers.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used CAS NO. 848133-35-7 in the treatment method of colorectal most cancers and compact cell lung most cancers.
3-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have various applications, together with antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for variety 2 diabetic issues that inhibits the enzyme DPP-4 to manage CAS NO. 875573-66-3 blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is associated with the synthesis of varied gluconic acid derivatives, which are used in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication applied to control form 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).